H2N2V1, Main, Exploration, bibRecord, 001D34

The HA1 of cold-adapted influenza B vaccine is not altered during replication in human vaccinees

Identifieur interne : 001D34 ( Main/Exploration ); précédent : 001D33; suivant : 001D35

The HA1 of cold-adapted influenza B vaccine is not altered during replication in human vaccinees

Auteurs : Seema Abbasi [États-Unis] ; William Gruber [États-Unis] ; Kathryn Edwards [États-Unis] ; Larisa Gubareva [États-Unis] ; Robert G. Webster [États-Unis] ; Yoshihiro Kawaoka [États-Unis]

Source :

Virus Research [ 0168-1702 ] ; 1995.

RBID : ISTEX:63F8C9D071893FAF2D51BD51C1EB57C155346A66

English descriptors

Abstract

Abstract: Influenza viruses recovered from 14 children 2–10 days after vaccination with an egg-grown, cold-adapted influenza B vaccine (B/AA/1/86) were analyzed. Hemagglutination-inhibition (HI) assays using monoclonal antibodies did not detect antigenic differences between the vaccine strain and the viruses recovered from the vaccinees. Furthermore, nucleotide sequence analysis of the HA1 region did not reveal any changes compared to the sequence of the vaccine strain. These findings indicate that influenza B vaccine hemagglutinin is genetically stable during replication in human vaccinees.

Url:

https://api.istex.fr/ark:/67375/6H6-FTLRD5GS-D/fulltext.pdf

DOI: 10.1016/0168-1702(95)00097-6

Affiliations:

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Abstract: Influenza viruses recovered from 14 children 2–10 days after vaccination with an egg-grown, cold-adapted influenza B vaccine (B/AA/1/86) were analyzed. Hemagglutination-inhibition (HI) assays using monoclonal antibodies did not detect antigenic differences between the vaccine strain and the viruses recovered from the vaccinees. Furthermore, nucleotide sequence analysis of the HA1 region did not reveal any changes compared to the sequence of the vaccine strain. These findings indicate that influenza B vaccine hemagglutinin is genetically stable during replication in human vaccinees.</div>
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The HA1 of cold-adapted influenza B vaccine is not altered during replication in human vaccinees

The HA1 of cold-adapted influenza B vaccine is not altered during replication in human vaccinees

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

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